Pefabloc® FG, Inhibitor for Fibrinogen
FG binds with a high affinity to fibrinogen, inhibits fibrin polymerization, modifies the mechanical properties of fibrin clots and can dissociate non-stabilized fibrin gels. Application:
FG is added to fibrinogen containing reaction mixtures to inhibit disturbing fibrin-related turbidity, gel formation and fibrin deposition in diagnostic and preparative procedures (e. g. measurement of thrombin generation in plasma). Pefabloc®
FG is also used to inhibit fibrin formation during purification and processing of clotting factors and other plasma proteins.Recommended Pefabloc® FG concentrations:
|human plasma, HC-II test
|bov. fibrinogen 0.2% / thrombin 0.5 U/ml
Formula: H-Gly-Pro-Arg-Pro-OH · AcOH
Solubility: readily soluble in water
May be used by the expiry date given on the label when stored unopened, protected from moisture, in the dark, 2-8°C. Avoid contamination of the reagents by micro-organisms. Shipment of product does not require cooling during the time of transportation.
Category: Research use only
Product Availability: Germany, Israel and Egypt
Manufacturer: DSM Nutritional Products Ltd. Branch Pentapharm, Switzerland
For more information please click .pdf icon below.
Inhibitor for Fibrinogen
Einheit: 1 g
Hersteller: Pentapharm AG
- Furlan M, Rupp C, Beck E A, Svendsen L.
Effect of calcium and synthetic peptides on fibrin polymerization. Thromb Haemost 1982; 47: 118-21.
- Prasa D, Svendsen L, Stürzebecher J.
The ability of thrombin inhibitors to reduce the thrombin activity generated in plasma on extrinsic and intrinsic Activation. Thromb Haemost 1997; 77: 498-503.