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Pefabloc® SC, Inhibitor for Proteinase

Pefabloc® SC is an irreversible proteinase inhibitor with broad specificity for serine proteinases.

Pefabloc® SC is suitable for biopharmaceutical downstream purification because of its superior solubility, stability, inhibitory activity and low toxicity.

Formula: C8H10FNO2S · HCl

MW: 239.7

Chem. Name:
4-(2-Aminoethyl)-benzenesulfonylfluoride hydrochloride (AEBSF)

Solubility: 200 mg/ml in H2O in water

May be used by the expiry date given on the label when stored unopened, protected
from moisture, in the dark, 2-8°C. Avoid contamination of the reagents by micro­
Shipment of product does not require cooling during the time of transportation.

IC50 values:
The following table shows IC50 values for a selection of enzymes determined at pH 7.0, 25 °C after 15 minutes incubation time.

Enzyme Enyzme conc.     IC50 [mM]
Trypsin 0.2 µg/ml 0.081
Chymotrypsin 2.44 µg/ml 0.044
Thrombin 0.079 µg/ml 0.92
Factor Xa 0.12 U/ml 24.0
Plasmin 4 CTA-U/ml 1.99
tPA 5.0 µg/ml 0.72
uPA 24.0 µg/ml 0.072
Glandular kallikrein 3.5 µg/ml 2.86
Elastase 2.44 µg/ml 0.525
Subtilisin A 0.49 µg/ml 1.801
Factor XIIa 0.013 U/ml 0.256

Category: Research use only

Type: Inhibitor

Product Availability: Germany, Israel and Egypt

Manufacturer: DSM Nutritional Products Ltd. Branch Pentapharm, Switzerland

For more information please click .pdf icon below.

Pefabloc SC

Inhibitor for Proteinase
Artikelnr.: 839901

Einheit: 10 g

Code: 399-01

Hersteller: DSM Nutritional Products Ltd. Branch Pentapharm

Pefabloc SC

Inhibitor for Proteinase
Artikelnr.: 839901/g

Einheit: 1 g

Code: 399-01

Hersteller: DSM Nutritional Products Ltd. Branch Pentapharm


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