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anti-human CD41, Clone MEM-06

CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, ß) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte­-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.

The monoclonal antibody ADG5026/L (clone MEM­-06) is a murine monoclonal antibody, subclass IgG1. The antibody has been purified from by protein­-A affinity chromatography, Purity > 95% (by SDS­-PAGE). The antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIbalpha (heavy chain; 120 kDa) and GPIIbß (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.

Vial containing 100 µg /100 µl (ADG5026) or 300 µg/ 300 µl (ADG5026L) of purified antibody in PBS containing 0.09 % sodium azide (pH 7.2). The IgG concentration is 1 mg/ml. Spin the vial briefly before opening.

Storage and Stability
Store at 4 °C. For long­term storage aliquot and store at -­20°. It is recommended to avoid freeze-thaw cycles. The reagent is stable until the expiry date stated on the vial label.

Flow Cytometry

Category: Research use only

Type: Antibody

Product Availability: Worldwide

Manufacturer: ImmBioMed GmbH & Co KG, Germany

For more information please click .pdf icon below.

anti-human CD41, Clone MEM-06

Cat.No. ADG5026
Artikelnr.: 938054

Einheit: 100 µg

Code: ADG5026

Hersteller: ImmBioMed GmbH & Co. KG


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  4. Zhang J, Varas F, Stadtfeld M, Heck S, Faust N, Graf
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