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anti-human CD41, APC-conjugated, Clone MEM-06

CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, ß) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte­platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.

The monoclonal antibody ADG5029/L (clone MEM­-06) is a murine monoclonal antibody, subclass IgG1. The antibody has been purified from by protein­-A affinity chromatography, Purity > 95% (by SDS­-PAGE). The antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIbalpha (heavy chain; 120 kDa) and GPIIbß (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.

The purified antibody is conjugated with cross­-linked Allophycocyanin (APC) under optimum conditions. The reagent is adjusted for direct use. No reconstitution is necessary.

Vial containing 500 µl (ADG5029) or 2 ml (ADG5029L) of purified antibody in PBS containing 1% BSA and 0.09% sodium azide (pH 7.2). The IgG concentration is 1 mg/ml. Spin the vial briefly before opening.

Storage and Stability
Store the antibody at 4°C. Avoid prolonged exposure to light. The reagent is stable until the expiry date stated on the vial label.

Flow Cytometry

Category: Research use only

Type: Antibody

Product Availability: Worldwide

Manufacturer: ImmBioMed GmbH & Co KG, Germany

For more information please click .pdf icon below.

anti-human CD41, APC-conjugated, Clone MEM-06

Cat.No. ADG5029L
Artikelnr.: 938064

Einheit: 2 ml

Code: ADG5029L

Hersteller: ImmBioMed GmbH & Co. KG


  1. Debili N, Robin C, Schiavon V, Letestu R, Pflumio F, Mitjavila­-Garcia MT, Coulombel L, Vainchenker W: Blood.
    2001 Apr 1;97(7):2023­-30.
  2. Mitjavila­-Garcia MT, Cailleret M, Godin I, Nogueira MM, Cohen­-Solal K, Schiavon V, Lecluse Y, Le Pesteur F, Lagrue AH, Vainchenker W: Development. 2002 Apr;129(8):2003­-13.
  3. Ferkowicz MJ, Starr M, Xie X, Li W, Johnson SA, Shelley WC, Morrison PR, Yoder MC: Development. 2003 Sep;130(18):4393­-403.
  4. Zhang J, Varas F, Stadtfeld M, Heck S, Faust N, Graf T: Exp Hematol. 2007 Mar;35(3):490­-499.

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