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anti-human CD147, PE-conjugated, Clone MEM-M6/1

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.

The monoclonal antibody ADG5088/L (clone MEM-M6/1) is a murine monoclonal antibody, subclass IgG1. The antibody has been purified from ascites using protein-A affinity chromatography, Purity > 95% (by SDS-PAGE).

The antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neur¬othelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. The antibody MEM-M6/1 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.

The purified antibody is conjugated with R-Phycoerythrin (R-PE) under optimum conditions. The reagent is adjusted for direct use. No reconstitution is necessary.

Vial containing 500 µl (ADG5088) or 2 ml (ADG5088L) of purified antibody in PBS containing 1% BSA and 0.09% sodium azide (pH 7.2). The IgG concentration is 1 mg/ml. Spin the vial briefly before opening.

Storage and Stability
Store the antibody at 4°C. Avoid prolonged exposure to light. The reagent is stable until the expiry date stated on the vial label.

Flow Cytometry

Category: Research use only

Type: Antibody

Product Availability: Worldwide

Manufacturer: ImmBioMed GmbH & Co KG, Germany

For more information please click .pdf icon below.

anti-human CD147, PE-conjugated, Clone MEM-M6/1

Cat.No. ADG5088
Artikelnr.: 938227

Einheit: 500 µl

Code: ADG5088

Hersteller: ImmBioMed GmbH & Co. KG


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