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anti-human CD147, Clone IT10C5

Emmprin (extracellular matrix metalloproteinase inducer) (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as CD147 or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell sur¬face expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.

The monoclonal antibody ADG5090/L (clone IT10C5) is a murine monoclonal antibody, subclass IgG1. The antibody has been purified from hybridoma ascites using protein-A affinity chromatography, Purity > 95% (by SDS-PAGE).

The antibody recognizes human Emmprin.

Vial containing 100 µg /100 µl (ADG5090) or 300 µg/300 µl (ADG5090L) of purified antibody in PBS containing 0.09 % sodium azide (pH 7.2). The IgG concentration is 1 mg/ml. Spin the vial briefly before opening.

Storage and Stability
Store at 4 °C. For long-term storage aliquot and store at -20°. It is recommended to avoid freeze-thaw cycles. The reagent is stable until the expiry date stated on the vial label.

Western Blotting (recommended concentration of 0.1 -10 µg/ml)
Western blot analysis of recombinant human Emmprin (1 µg) using the monoclonal antibody IT10C5

Research use only

Type: Antibody

Product Availability: Worldwide

Manufacturer: ImmBioMed GmbH & Co KG, Germany

For more information please click .pdf icon below.

anti-human CD147, Clone IT10C5

Cat.No. ADG5090
Artikelnr.: 938236

Einheit: 100 µg

Code: ADG5090

Hersteller: ImmBioMed GmbH & Co. KG

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