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TAFI (Thrombin Activatable Fibrinolysis Inhibitor) - White Paper

18.08.2022

As a researcher in hemostasis you might be interested in latest scientific information on TAFI (Thrombin Activatable Fibrinolysis Inhibitor).

TAFI is activated by Thrombin and plays an important role in hemostasis and fibrinolysis.
Current research has provided evidence for the importance of TAFI in certain clinical conditions:

  • The role of TAFI in acute myocardial infarction (AMI)
  • Association with Acute Pulmonary Embolism
  • Delayed fibrinolysis in connection with coinherited TAFI deficiency
  • The bleeding phenotype in patients with severe hemophilia A
  • Plasmin generation on thrombin-activated platelets
  • As a target for anti-thrombotic therapy
  • Vascular remodeling after hemophilic joint bleeding
  • Certain forms of inflammation

We have compiled an updated White Paper with scientific TAFI publications and information on our TAFI Activity Assay.
This assay is a functional chromogenic assay for the determination of Thrombin Activatable Fibrinolysis Inhibitor (TAFI), which has been widely used by the scientific community in specialty coagulation research and development.

If you are interested in this information compilation please send an email to info@loxo.de. We will be happy to provide this to you.


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